… Toxoplasma gondii is a common protozoan parasite that infects a … for the parasite's survival.
Here we examined the … Among the aforementioned pathways of fatty acid biogenesis, FAS2 …

… Although the FASII fatty acid biosynthesis pathway located in the apicoplast is essential for
parasite survival, the cellular … loss and defects in its morphology and biogenesis along the T. …

… and Toxoplasma gondii both belong to this phylum and are … /organelle biogenesis, and
parasite survival and propagation. … is a major apicoplast product essential for the parasite survival …

… fatty acid synthesis pathway (FASII). These fatty acids are either exported out of the apicoplast
… cyst-forming apicomplexan parasites such as Toxoplasma gondii and Neospora caninum. …

… essential combination of fatty acids (FAs), obtained from de novo synthesis and host … in
the cytosol of the parasites enter the apicoplast via the apicoplast phosphate transporter (APT). …

… synthesis pathway within the apicoplast, the type II fatty acid (… the survival and replication of
parasites without an apicoplast in the … , Plasmodium falciparum and Toxoplasma gondii. Two …

… pathways by which these parasites can obtain the nutrients essential for their survival is an
… during its intracellular development for membrane biogenesis, proper lipid homeostasis, and …

… membrane biogenesis. However, it is not known to what extent fatty acids generated by the
apicoplast … Since the apicoplast is essential for parasite survival, some of these pathways are …

… fatty acids killing the parasite. On the other hand, the downregulation of TgLIPIN induced a
significant reduction of the apicoplast … of 7 enzymes in Toxoplasma gondii as putative acyl-…

… apicoplast of Toxoplasma gondii. Many glycolytic enzymes in … precursor and fatty acid
synthesis in the apicoplast. As such, … is essential for apicoplast maintenance and parasite survival. …